Early manifestations and differential gene expression associated with photoreceptor degeneration in Prom1-deficient retina
Retinitis pigmentosa (RP) and macular dystrophy (MD) are characterized by gradual photoreceptor death in the retina and are often associated with genetic mutations, including those in the prominin-1 (Prom1) gene.Prom1-knockout (KO) mice recapitulate key features of these diseases including light-dependent retinal degeneration and constriction of Sw